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Further, when THBP was co-incubated with either NAC, NACET, or diNAC (two NAC molecules bridged via disulfide bond, masking the active thiol) for 9 h, a concentration-dependent reduction in ROS generation was observed (Fig

Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: A phase 2, randomised, double-blind, non-inferiority trial

The reactive metabolites may also alter liver proteins leading to an immune response and immune-mediated injury

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