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Tension is a big factor in wound dehiscence and hypertrophic [raised, thick, red] scarring, and this [helps prevent both with] a tension-free closure. Reconnecting each tissue layer that was cut, from the bottom up, also keeps the skin from sticking down to the fascia and creating tethered scars (like those seen after C-sections)

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction