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The United Kingdom (UK) and the Netherlands have only approved GLP-1s for people with BMIs above 30 and 35, respectively

Sources: healthcare.utah.edu University of Utah Health Newsroom: Ozempics popularity and lean mass loss concerns healthcare.utah.edu University of Utah Health HealthFeed: Body composition basics and muscle loss during weight loss pmc.ncbi.nlm.nih.gov Journal of Endocrine Society (STEP1 Trial Analysis): Semaglutide ~15% weight loss vs placebo technologynetworks.com Technology Networks Ozempic Could Impact Strength: 15% weight loss with ~45% from lean mass advances.massgeneral.org Mass General Brigham Advances in Motion: High-protein diet + exercise preserves muscle on GLP-1 therapy obesityaction.org Obesity Action Coalition Body Composition Guide: Importance of checking fat vs muscle during weight loss drugs.com Drugs.com Semaglutide cost FAQ: Typical monthly cost of Wegovy without insurance

As treatment continues and the plan is adjusted, patients may begin to notice changes in portion sizes, cravings, clothing fit, and overall weight

Patience is essential because semaglutide efficacy builds over weeks, not days