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Documented Reduction in Paresthesia and Burning Sensations High-dose B12 therapy reduces paresthesia and burning in diabetic neuropathy

All that remains to be seen, and an absolute benefit of 1.5 per 100 people treated is certainly nothing to write home about

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Similarly, patients with active malignancy warrant careful consideration given theoretical concerns about angiogenic effects potentially affecting tumor growth, though preclinical evidence suggests context-dependent effects that may inhibit rather than promote tumor angiogenesis