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Saxenda is suitable for patients who are: Overweight (BMI equal to greater than 27) with at least one weight-related medical problem such as high cholesterol levels, hypertension, and type 2 diabetes Obese (BMI equal to or greater than 30) It is also indicated for children aged 12 or more with a body weight above 60 kg or 132 pounds

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Subsequent GLP1RA trials including LEADER and SUSTAIN-6 had small populations of patients with established HF, therefore limiting any potential generalizations about HF risk with GLP1RA (54,55)

2017 (9) studies suggest that when cells encounter oxidative stressmarked by excess free radicalsthis imbalance may trigger several defensive responses within the cell