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Published research in animal models has explored Melanotan II in the context of: Mechanism of Action Melanotan II acts as a non-selective agonist at the melanocortin receptors (MC1R, MC3R, MC4R, and MC5R)

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It is a natural skin protectant with anti-inflammatory properties that help protect skin from environmental agents that contribute to dark spots, rough dry skin, uneven skin tone, sun damage, collagen breakdown, and clogged pores and breakouts

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Lowman X.H., Hanse E.A., Yang Y., Gabra M.B.I., Tran T.Q., Li H., Kong M