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Accordingly, copper may preferentially accumulate in this tissue, potentially facilitating activation of the copper-induced cell death pathway

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Also, optical/physical radiations (ultraviolet, visible light, infrared) as well as systemic drugs (chloroquine, fluphenazine, physostigmine, imatinib) and topical drugs (imiquimod, long-term use of topical steroid) have been reported as vitiligo promoters (Harris 2017

Huang et al., 2015), much like it is effective also in counteracting bleeding disorders (Stupnisek et al., 2012