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Our study has limitations that need to be acknowledged including the retrospective study design and the relatively small sample size despite screening an initial cohort of over 1000 samples sent for ammonia testing
Acknowledgements The authors acknowledge the support of grants from Inserm, CNRS, Universit Paris Cit, Agence Nationale de la Recherche (ANR), Socit Francophone du Diabte (SFD), Fondation pour la Recherche Mdicale (FRM), the Dutch Organization for Scientific Research (ZonMW) and DiabetesFonds
According to reports, after 24 hours of treatment with celecoxib, an increase in its concentration can enhance the levels of HO-1 mRNA and protein expression in endothelial cells of humans, and the bilirubin content reaches its highest level after 48 hours of celecoxib treatment