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Theyve also been shown to decrease the risk of hospitalizations due to heart failure and reduce the occurrence of irregular heart rhythms
Protocol 1: Maximum weight loss (30+ pounds to lose) Goal: Lose as much fat as possible, as safely as possible Stack: Semaglutide OR Tirzepatide: Standard titration protocol Optional add: CJC-1295/Ipamorelin (muscle preservation) High protein diet: 1g per pound goal body weight Resistance training: 3x per week Duration: 6-12 months Expected results: 30-60 pounds fat loss Muscle maintained or slightly increased Metabolic health dramatically improved Why this works: GLP-1 handles appetite
Other drugs in this class include liraglutide (Saxenda) and exenatide (Byetta)
Chugai's medicinal chemistry effort identified a series of non-peptide compounds that activated the GLP-1 receptor with nanomolar potency through a previously unrecognized binding pocket
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