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Further large-scale, randomised controlled trials with longer follow-up are needed before these medications can be considered an evidence-based treatment option for alcohol use disorder

Food and Drug Administration (FDA) (2017) Medullary thyroid carcinoma, an uncommon cause of thyroid nodules but an important cause of thyroid neoplasms, Mayo Clinic Proceedings (1992) Glucagon-like peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus, JAMA Internal Medicine (2013) Semaglutide and cardiovascular complications in patient with type 2 diabetes mellitus, The New England Journal of Medicine (2016) Association of glucagon-like peptide-1 receptor agonist use with risk of gallbladder and biliary diseases, JAMA Internal Medicine (2022) Diabetic retinopathy, Mayo Clinic (2023) Semaglutide, reduction in glycated hemoglobin and the risk of diabetic retinopathy, Diabetes, Obesity, and Metabolism (2018) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

Tolerability focus: Both cause GI effects

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