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Indeed, the SELECT trial demonstrated that semaglutide reduced major adverse cardiovascular events (MACE) by 20% despite the modest heart rate increase

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[12] [1] If pancreatitis is suspected (persistent, severe abdominal pain), Rybelsus should be discontinued immediately and urgent medical assessment sought

Both were conducted in patients who had type 2 diabetes as well as lupus, which is the population in which these drugs were being prescribed