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(2004) 287:C81733

Keywords: GERD, NERD, LPR, diagnosis, treatment, PPIs, mucosal protection, hyaluronic acid, chondroitin sulphate, medical devices Plain language summary Medical devices with esophageal mucosal protective activity for the management of GERD Gastro-esophageal reflux disease (GERD), a condition where stomach acid or food flows back into the esophagus, is highly prevalent in the Western world and strongly impairs quality of life

The released thio-glucose was catalyzed by GOx into cytotoxic HS while preserving H2O2, leading to disruption of the mitochondrial electron transport chain and dissipation of the mitochondrial membrane potential