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On the other hand, the lack of monoamine oxidase (MAO) activity, enzymes involved in the oxidative deamination of mitochondrial monoaminergic neurotransmitters such as dopamine, serotonin, tyramine, and norepinephrine, would also result in the accumulation of these neurotransmitters (154)

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Diabetic retinopathy complications have been reported, particularly in patients with pre-existing retinopathy experiencing rapid improvements in glycaemic control

These insights help identify whether semaglutide, tirzepatide, or dual-peptide protocols align with your individual genetic predispositions for optimal response