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Indeed, it is possible for them to modify the composition of the indigenous gut microbiota, resulting in a subsequent modification of the gut lumen that promotes a more advantageous anti-inflammatory environment (Suez et al., 2018)

It might not just be the stress or lack of sleep you're attributing it to

This is because, like many antidepressants, supplementary 5-HTP raises the amount of serotonin in the brain, so the combination could result in dangerous levels of the neurotransmitter.8 39 With that being said, lets take a look at how 5-HTPs ability to boost serotonin could be beneficial for those dealing with PMDD

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