Nutr Res 35(8):707715 Askarpour M, Hadi A, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E (2020) Beneficial effects of L-carnitine supplementation for weight management in overweight and obese adults: an updated systematic review and dose-response meta-analysis of randomized controlled trials
Hair Growth Disruptors and Hair Loss These factors can shorten the anagen phase , trigger premature telogen shedding , and weaken the hair follicle, leading to hair loss or thinning : Physical Stress on the Scalp Tight hairstyles (ponytails, braids, extensions) traction alopecia Aggressive brushing or frequent heat styling Overuse of harsh chemical treatments (bleaching, perms, relaxers) Emotional & Psychological Stress High cortisol levels from chronic stress can push hair into the telogen phase (telogen effluvium) Anxiety and sleep deprivation negatively affect follicle function Poor Nutrition Low protein intake hair is made of keratin (a protein) Deficiencies in iron, zinc, biotin, vitamin D, B12 , omega-3s Crash dieting or calorie restriction disrupts follicle energy supply Hormonal Imbalances High DHT (dihydrotestosterone) levels shrink follicles androgenetic alopecia Thyroid disorders (hypothyroidism, hyperthyroidism) PCOS (Polycystic Ovary Syndrome) in women Menopause or postpartum hormonal shifts Medications That Affect Hair Growth Antidepressants (e.g., SSRIs) Blood pressure meds (beta blockers, ACE inhibitors) Isotretinoin (used for acne) Chemotherapy Birth control pills (starting or stopping) Lifestyle & Environmental Factors Smoking reduces blood flow to hair follicles Alcohol abuse interferes with nutrient absorption UV radiation from sun exposure damages the scalp Air pollution and toxins can cause oxidative stress on follicles Genetic Conditions & Autoimmune Disorders Alopecia areata : the immune system attacks hair follicles Lupus and other systemic inflammatory conditions Trichotillomania : hair-pulling disorder How Can I Stimulate Hair Growth
GLP-1s make that deficit easier to sustain
Furthermore, therapeutic drugs targeting Th17/Treg balance, including conventional and alternative therapies currently used in clinical practice, as well as emerging drugs under investigation, are reviewed
