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Animal studies showed no evidence of impaired fertility or fetal harm, however at 600 mg/kg daily there was a statistically insignificant increase in post implantation losses

Tirzepatide generally produces greater average weight loss in clinical trials, with the SURMOUNT-1 trial showing up to 22.5% body weight reduction at the highest dose compared to semaglutide roughly 15-17% in comparable trials

2023 May 1;