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In practice, optimal intranasal dosing is often established through a combination of in vivo pharmacokinetic studies, brain-to-plasma exposure ratios, and pharmacodynamic endpoints, rather than relying solely on systemic dose equivalence (Dhuria et al., 2010)

Key Takeaway: BPC-157 supports the gut through "angiogenesis" (forming blood vessels) and protecting the "tight junctions" of the intestinal lining, which helps maintain a strong barrier between your gut and the rest of your body