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Postmarketing surveillance in countries where cerebrolysin has been used for decades has not revealed unexpected long-term safety signals, but formal long-term controlled studies are lacking

Thus, NACs neuroprotective effects may involve its ability to reduce cortical spermidine levels and thereby limit local excitotoxic effects in the PFC during THC exposure, further indicated by our electrophysiological findings demonstrating a hyperactive neuronal mPFC phenotype

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