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Over the past 30 yr, several methods for modifying the toxicity of paraquat have been examined: a) prevention of absorption by the gastrointestinal tract (2, 3), b) removal from the bloodstream (1, 4), c) prevention of accumulation in the lungs (5, 6), d) scavenging oxygen free radicals (7), and e) prevention of lung fibrosis (8, 9)