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It is also almost impossible to determine whether the oral mucosal melanin hyperpigmentation in an HIV-seropositive smoker who is on multiple drug therapy is owing to the medication, to the HIV infection, to the use of tobacco, or to the interaction between these factors
This indicates that their cardiometabolic benefits are primarily mediated by weight loss, IR alleviation, and improvements in triglyceride-rich lipoprotein pathways, rather than a direct reduction in LDL-C levels
It is a remarkably effective antioxidant around 100 times more effective than vitamin C at eliminating free radicals [11, 12]
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