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Scientific References: Dou Y, Lee A, Zhu L, Morton J, Ladiges W., Aging Pathobiology and Therapeutics , 2020

Dai X, Ding Y, Zhang Z, Cai X, Li Y (2013) Quercetin and quercitrin protect against cytokine-induced injuries in RINm5F -cells via the mitochondrial pathway and NF-B signaling

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Genetical evidence from key studies confirms that eliminating GPX4 expression via genetic knockout in various cell types, or directly targeting its active site with small molecule inhibitors like RSL3, consistently and efficiently induces typical ferroptosis (Wang L