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In addition to its catalytic abilities, the latter also contributes to the maintenance of the reactants in a weakly reducing environment

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According to the SUSTAIN 6 trial, the average increase in heart rate is between 2.75-3.2 beats per minute (bpm), which is clinically insignificant. While the average heart rate increase is between two and three beats per minute, some individuals have experienced an increase of up to 10 bpm in resting heart rate after administering a 1.5 mg dose of semaglutide

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