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Agents in this group include peroxisome proliferator-activated receptor agonists (e.g., pioglitazone, elafibranor, saroglitazar), bile acid-farnesoid X receptor axis regulators (obeticholic acid), de novo lipogenesis inhibitors (aramchol, NDI-010976), and fibroblast growth factor 21/19 analogs

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At 2.4 mg, weight typically stabilizes at a new set-point rather than declining indefinitely that is the expected, documented behavior, not a stall to fix by exceeding the labeled maximum