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Both SP and L-car attenuated DOX-induced ovarian oxidative damage, subsequent ovarian mtDNA expression, and activation of downstream inflammatory and apoptotic pathways, particularly lowering P53 and caspase-3 protein expressions in preantral follicles, thus preventing ovarian insult and follicle demise and extending the post-chemotherapy fertile period

RG7388 (idasanutlin), a nutlin derivative, has greater selectivity and efficacy than RG7112, an MDM2 inhibitor

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Immune Support : Adequate glutathione levels are essential for optimal immune function, helping to combat infections and diseases