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Common Side Effects (Both Drugs) Nausea (most common, worst during dose escalation) Diarrhoea Constipation Vomiting Abdominal pain Fatigue Injection site reactions Most gastrointestinal effects improve significantly after the first 48 weeks

This class of compounds binds to key receptors in the brain, pancreas, and gastrointestinal (GI) tract, instigating several biological reactions: Enhances insulin secretion Slows gastric emptying Increases -cell proliferation Reduces glucagon release Mitigates hunger signaling These actions combine to regulate appetite, food intake, and the physical feeling of fullness (satiety)

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