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Efficacy and Safety of Dulaglutide Monotherapy Compared With Glimepiride in East-Asian Patients With Type 2 Diabetes in a Multicentre, Double-Blind, Randomized, Parallel-Arm, Active Comparator, Phase III Trial

Although AREDS2 revealed that no significant decrease was observed in the risk of advanced AMD for lutein/zeaxanthin, subgroup analyses showed that for participants in the lowest quintile of dietary intake (mean = 696 g/day), lutein/zeaxanthin exhibited protective effects against AMD progression possibly because the lutein/zeaxanthin consumption of the individuals was similar to that of other well-nourished groups [103]

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Variants in GLP1R, GIPR, FTO, and MC4R genes correlate with differential metabolic responses and appetite regulation