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Sodiumglucose cotransporter-2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) both improve cardiovascular outcomes, but their comparative roles in HF and the potential value of combination therapy remain uncertain

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Coutinho T., Borlaug B.A., Pellikka P.A., Turner S.T., Kullo I.J

Orlistat works by reducing fat absorption rather than affecting appetite hormones, but it's important to note that it commonly causes gastrointestinal side effects (including steatorrhoea and urgency) and is contraindicated in chronic malabsorption conditions and cholestasis