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Tschen et al reported increased proliferation of duct cells in response to exendin similar to that found in beta cells (117)

The most common subcutaneous injection sites are: Abdomen: at or under the level of the belly button, about 1.5 inches away from the navel Upper arm: back or side of the upper arm, about 3 inches above the elbow and 3 inches below the shoulder Upper thigh: front or side of the upper thigh If youre self-administering your subcutaneous injection, this should be done in the abdomen or upper thigh only

That mechanism is directly relevant for a population managing high rates of metabolic disease where weight is both a driver and a consequence of other conditions

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