However, a thoughtful plan that includes protein support, resistance training, and regular clinical oversight can meaningfully reduce risk
L cells express the surface receptor TGR5, and TGR5 agonists such as 6-ethyl-23(S)-methylcholic acid (EMCA, INT-777) can induce GLP-1 release, modulating insulin secretion and delaying gastric emptying
The broader benefits of GLP-1 therapyincluding improvements in body composition, insulin resistance, cardiovascular risk factors, sleep apnea, and overall metabolic healthcan all positively influence reproductive function. Because infertility, obesity, metabolic syndrome, and low testosterone frequently coexist, treating the underlying metabolic disease may have substantial downstream reproductive benefits
To add to that, a study published by Doctors Without Borders/Mdecins Sans Frontires (MSF) earlier this year, found that unavailability coupled with limited access due to high costs already affect patients in these countries