While in the foregoing specification this invention has been described in relation to certain embodiments thereof, and many details have been put forth for the purpose of illustration, it will be apparent to those skilled in the art that the invention is susceptible to additional embodiments and that certain of the details described herein can be varied considerably without departing from the basic principles of the invention
High-dose PLGA-encapsulated IGF-1 LR3 at 280 g produced statistically significant increases in muscle wet weight at 28 days post-implantation compared to vehicle controls
Bailey CP, Figueroa M, Gangadharan A, Yang Y, Romero MM, Kennis BA, Yadavilli S, Henry V, Collier T, Monje M, Lee DA, Wang L , Nazarian J, Gopalakrishnan V, Zaky W, Becher OJ, Chandra J
However, these direct mechanisms require further confirmation in human studies