Although liraglutide-induced changes in gut microbiota composition are heterogeneous across studies, consistent enrichment of metabolically beneficial taxa, particularly Akkermansia muciniphila, Lactobacillus , and Bifidobacterium , along with a reduction of obesity-associated genera emerges as a reproducible pattern, highlighting that species-level and functional alterations are more informative than phylum-level shifts (27, 44)
In one study, people who switched to tirzepatide after being on another GLP-1 medication continued to lose weight (about 2.1 kg more in 12 weeks) instead of plateauing
I absolutely recommend that patients who have successfully lost weight clean out their entire closet, she says
Gonnissen HK, Hursel R, Rutters F, Martens EA, Westerterp-Plantenga MS