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Early studies show that retatrutide does not only act on the glucagon receptor

conducted a retrospective study of 42 women with obesity who had used GLP1RAs for six months pre-pregnancy, but with an eight-week withdrawal before pregnancy, compared with women with obesity who chose to manage their weight with diet and exercise, and found that women who had been using GLP1RAs pre-pregnancy had reduced GWG compared to the diet and exercise group [30]

Of course, there are other contributing factors to obesity in these studies

And then when youre filled up, it stores it for later use. When the body doesnt produce enough insulin or use insulin efficiently, we can gain weight, according to Cleveland Clinic