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Description

To guarantee safety, efficacy, and suitability, UK clinicians must examine, prescribe, and monitor their usage

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Patients with GI sensitivity: While orforglipron's GI side effect profile is broadly similar to injectable GLP-1s, the daily oral dosing means the GI tract is exposed to the active compound on a different kinetic schedule than weekly injections

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Maintenance dosing at 1.7mg2.5mg weekly

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Rawson ES, Clarkson PM, Price TB, Miles MP

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