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SIRT1 may reduce NET formation by deacetylating FOXO1 and increasing the expression of the pro-apoptotic protein Bim, which destabilizes mitochondrial membranes by interacting with anti-apoptotic members of the Bcl-2 family and shortens neutrophil survival, limiting their accumulation in liver tissue

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La vitamina C se encuentra en los ctricos, y tambin tiene propiedades antioxidantes, ya que puede expulsar a los radicales libres del organismo y ayudar a proteger los tejidos del estrs oxidativo

Moreover, alterations in the activity or concentration of cystathionine -synthase and cystathionine -lyase have been associated with various pathological conditions and diseases, including diabetes, cancer, AIDS, neurodegenerative disorders, and liver diseases [29, 30, 31]