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[20] The MHRA will be responsible for evaluating any future marketing authorisation application for retatrutide across the UK

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Commonly prescribed GLP-1 receptor agonists in the UK include: Semaglutide (Ozempic, Wegovy, Rybelsus [oral formulation]) Dulaglutide (Trulicity) Liraglutide (Victoza, Saxenda) Exenatide (Byetta [twice-daily], Bydureon [weekly]) Tirzepatide (Mounjaro) - a dual GIP/GLP-1 receptor agonist with similar considerations [6] [7] These medications are typically administered via subcutaneous injection (daily, twice-daily or weekly depending on the specific formulation), with semaglutide also available as an oral tablet