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Most are gastrointestinal and occur as your body adjusts to the medicine

Pediatr Res 38:324331 Poorthuis BJ, Jille-Vlckova T, Onkenhout W (1993) Determination of acylcarnitines in urine of patients with inborn errors of metabolism using high-performance liquid chromatography after derivatization with 4-bromophenacylbromide

Therefore, LL-37 gets tightly attached to bacteria, and the peptide inserts itself into the lipid bilayer and disrupts its structure, causing the membrane to leak essential ions and metabolites, leading to rapid cell death

The upside potential of these drugs is exciting, but it is important to recognize challenges that must be overcome to fully achieve anticipated impacts