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1 A review article of multiple randomized controlled trials reports an average weight loss of around 16% among users, with some losing as much as 17.4%

Molecular mechanisms underlying the impact of GLP-1RAs on cancer risk The regulation of cancer risk by GLP-1RAs involves several biological mechanisms, primarily encompassing metabolic regulation, direct anti-tumor effects, immune modulation, and epigenetic alterations

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Notably, the report suggested that semaglutide might improve obesity-associated subclinical neurodegeneration and might promote the regeneration of small corneal nerve fibers, indicating a potential neuroprotective effect during treatment