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5 Yellow River Basin Cross-Regional Acupuncture Data Open Application Laboratory, Jinan, Shandong, Peoples Republic of China *These authors contributed equally to this work Correspondence: Shaozong Chen, Yellow River Basin Cross-Regional Acupuncture Data Open Application Laboratory, Jinan, Shandong, Peoples Republic of China, Email [email protected] Abstract: Gastroesophageal reflux disease (GERD) is a common clinical digestive disorder with a complex pathological mechanism