Medical and pharmacy claims cost for users of Wegovy and Zepbound (treatment group) vs control over 18 months , compared to control group
In the STEP 3 trial of semaglutide combined with intensive lifestyle intervention (30 counseling visits across 68 weeks, including nutrition, physical activity, and other behavioral strategies, plus 8 initial weeks of meal replacements with liquid shakes, meal bars, or portion-controlled meals), individuals experienced a 16% reduction from baseline in body weight (versus 5.7% with intensive lifestyle intervention alone) [178]
GLP-1 weight loss costs are expected to increase again between approximately 130 percent (low estimate) and nearly 200 percent (high estimate), by the end of the second quarter in fiscal year 2027, according to the departments budget request
Be aware of potential risks and side effects Although peptides are generally safe, there are some critical factors to note: Injection site irritation : You may experience swelling, redness, or itching
