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The company has also raised doubts about the quality of compounded drugs, which are not reviewed premarket by the FDA

Mice on a high-fat diet were observed to have an increase in central 5-HT, which may partially contribute to the faster satiating effect of a calorie-dense diet [63]

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The most common side effects include nausea (occurring in up to 44% of patients at weight-loss doses), vomiting (up to 25%), diarrhea (up to 30%), abdominal pain, and constipation