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However, that higher use could save an estimated $18.2 billion in health care treatment costs, resulting in a net increase of $47.7 billion

doi: 10.1111/j.1365-2133.1986.tb06651.x

Pregnancy and breastfeeding are contraindications, as safety data in these populations remain limited

Another similar study looked at the acute hormonal and performance responses to resistance exercise with and without consumption of an amino acid/creatine/energy supplement (7)