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doi: 10.1016/j.mce.2017.06.002 224 MarquesPSkorupskaiteKGeorgeJTAndersonRA

A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]

It is still investigational and not approved anywhere, with possible FDA approval around 2027 (GoodRx)

Low testosterone levels can severely affect the health of aging males, increasing the risk of diabetes [9, 10], dementia [11], cardiovascular disease [12], and mortality [13]