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As with other chronic diseases, treatment should be viewed as long-term, similar to diabetes and hypertension

When there's excessive anything in a given pathway (especially something as toxic as glutamate), the brain responds by reducing sensitivity and/or # of receptors

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It stimulates the release of other hormones, such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are involved in the production of sex hormones and the development and maturation of eggs and sperm