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In vitro , glutamine supplementation upregulates claudin-1, occludin, and ZO-1 in Caco-2 monolayers, while glutamine deprivation or inhibition of glutamine synthetase increases permeability and reduces TEER (DeMarco et al., 2003

In a clinical trial comparing S-Acetyl-L-glutathione with a marketed GSH product, S-Acetyl-L-glutathione exhibited high tolerability and safety among participants

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