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To bridge this knowledge gap, future studies would need to focus on developing and validating already established clinically relevant animal models on large animals that better reflect human disease and allow for the study of long-term outcomes and tissue repair to set the stage for future human trials (Gonzalez et al., 2015

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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.McElroy S.L., Keck P.E

Compound profile Key research areas 01 Triple Receptor Agonism Retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, a mechanism studied for its compounding effects on energy balance and metabolic regulation beyond single or dual agonist compounds