Most of the time, constipation with Mounjaro is mild
The ones who struggle are often eating through the signal (usually palatable processed foods that don't trigger fullness the same way whole foods do)
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Frequencies reflect SmPC classifications: Very common (more than 1 in 10 people): nausea, vomiting, diarrhoea, decreased appetite, particularly during dose escalation Common (up to 1 in 10 people): increased heart rate, injection-site reactions, fatigue, constipation, dyspepsia, abdominal discomfort Uncommon to rare but clinically important: acute pancreatitis, gallbladder disease (including cholelithiasis and cholecystitis) Additional safety considerations per the UK SmPC include: Hypoglycaemia : the risk rises when tirzepatide is used with insulin or a sulfonylurea