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Methionine is an essential proteinogenic amino acid and also the precursor of S-adenosylmethionine (SAM), the universal reactive methyl donor in biochemical reactions (Kharbanda et al., 2005)

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Indeed, there is almost a complete overlap between NAFLD and MASLD populations in several epidemiological studies, while only 5.3% of individuals with NAFLD did not fulfil the MASLD criteria in the population-based Nutrition Examination Survey (NHANES III) [6, 8]

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