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Mutations identified in patients with defective lipoic acid metabolism affect genes involved in the synthesis of iron-sulfur clusters and genes coding for lipoic acid synthetase ( LIAS ), lipoyl transferase 1 ( LIPT1 ), and dihydrolipoamide dehydrogenase (E3 component of -ketoacid dehydrogenase complexes
doi: 10.1016/j.jfca.2021.103913 CrossRef Full Text | Google Scholar Morris, C
Glutathione amplifies the body's natural antioxidant defenses, acting as a cofactor for protective enzymes while regenerating oxidized vitamins C and E
Vitamin C has a well-established safety profile with decades of research supporting its long-term use when properly formulated
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