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Along with research released in May that found GLP-1 users were less likely to see some obesity-related cancers spread, University of Pennsylvania researcher Elizabeth McDonald said her study linking breast cancer prevention to GLP-1 drugs should "only increase the possibility there's a real biological signal" that should be studied in a robust clinical trail

This has the potential to modulate downstream signalling by directing the ligand towards GLP-1Rs situated in sub-microscopic membrane domains variably enriched with signalling effectors on the cytoplasmic side (Villar et al ., 2016)

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