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Of particular note: phentermine and other sympathomimetic agents must not be used with monoamine oxidase inhibitors (MAOIs) , and caution is required when combining them with other stimulants or serotonergic medicines
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However, a 2022 study in the journal Nutrients found that one of the ingredients in Lemme, Morosil red orange fruit extract, helped participants lose a small amount of weight though notably while also eating a healthy diet and exercising compared to those taking a placebo
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